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Nitric oxide (By breathing)

Nitric Oxide (NYE-trik OX-ide)

Treats breathing problems in newborn babies.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Your child's doctor will determine if this medicine should not be used for any reason.

How to Use This Medicine:


  • A nurse or other health professional will give your baby this medicine in a hospital. It is inhaled into the lungs through the mouth or nose.
  • This medicine is sometimes given through a face mask. It also may be given inside a plastic tent that is placed over the baby. The medicine is put into the air of the tent for breathing.
  • This medicine may need to be given for up to 14 days.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how nitric oxide works. Tell your child's doctor if your child is using nitroglycerin, prilocaine, or sodium nitroprusside.

Warnings While Using This Medicine:

  • Tell your child's doctor if your baby has heart problems, heart failure, or lung or breathing problems.
  • This medicine may cause a rare blood disorder called methemoglobinemia.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blue lips, pale skin
  • Chest pain, trouble breathing or fast, noisy breathing
  • Lightheadedness, dizziness, or fainting

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 3/19/2020

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