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Incobotulinumtoxina (By injection)

IncobotulinumtoxinA (in-koe-bot-ue-LYE-num-tox-in-ay)

Treats muscle spasms in the neck, eyelids, and upper arms. Also improves the appearance of deep facial lines or wrinkles.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to incobotulinumtoxinA, other botulinum toxin products, or human albumin.

How to Use This Medicine:


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • A nurse or other health provider will give you this medicine.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how incobotulinumtoxinA works. Tell your doctor if you are also using a muscle relaxer or an antibiotic, especially one that you use in your eye or that is injected.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have eye problems, trouble swallowing or breathing, an infection, or a nerve or muscle disorder, including ALS (Lou Gehrig disease), Lambert-Eaton syndrome, myasthenia gravis, or a cranial nerve disorder. Tell your doctor if you had surgery where the injection will be given.
  • This medicine may cause the following problems:
    • Symptoms similar to botulism, which could be life-threatening and occur weeks after treatment
    • Reduced blinking, which could lead to ulcers or other damage to the cornea
  • Tell your doctor if you have previously received botulinum toxin for any reason.
  • This medicine may cause vision problems or muscle weakness. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • This medicine is made from donated human blood. Some human blood products have transmitted viruses, although the risk is low because donors and blood are both tested for viruses. Talk with your doctor if you are concerned.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Eye pain, severe irritation, severe trouble seeing, double vision, vision problems that do not go away
  • Incontinence or leaking from the bladder
  • Trouble swallowing, breathing, or speaking
  • Unusual weakness or tiredness

If you notice these less serious side effects, talk with your doctor:

  • Drooping eyelids
  • Dry mouth
  • Pain, swelling, or bruising where the shot was given
  • Reduced eye blinking

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 7/4/2018

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.

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