Antihistamine/decongestant (By mouth)
Treats stuffy nose, sneezing, runny nose, and sinus congestion caused by hay fever, colds, or flu.
Acta-Tabs PE, Acticon, Actifed Cold & Allergy, Ala-Hist PE, Allegra-D, Allegra-D 12 Hour, Allegra-D 12 Hour Allergy & Congestion, Allegra-D 24 Hour Allergy & Congestion, Allegra-D 24HR, Allergy & Congestion Relief, Allergy Plus Sinus, Allergy Relief Nasal Decongestant, Allergy Relief-D, Antihistamine & Nasal Decongestant, AprodineThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:
You should not use this medicine if you have had an allergic reaction to any antihistamine or decongestant, or if you have used an MAO inhibitor (such as Nardil®, Marplan®, or Parnate®) within the past 14 days. Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years old. Using these medicines in very young children might cause serious or possibly life-threatening side effects.
How to Use This Medicine:
Thin Sheet, Capsule, Long Acting Capsule, Tablet, Long Acting Tablet, Chewable Tablet, 24 Hour Tablet, Dissolving Tablet, Liquid, Drop
- Your doctor will tell you how much medicine to use. Do not use more than directed.
- Follow the instructions on the medicine label if you are using this medicine without a prescription.
- Completely chew the chewable tablet before swallowing it. Swallow the regular tablet, regular capsule, extended-release tablet, or extended-release capsule whole. Do not crush, break, or chew it.
- If you use a powder, stir the medicine into water and drink it right away. Do not keep any unused mixture to take later.
- If you are using the Softchew®, you may let it melt in your mouth, or you may chew it. If you are using the dissolving tablet, let the tablet melt in your mouth.
- Measure the oral liquid medicine with a marked measuring spoon, medicine cup, oral syringe, or medicine dropper.
- You might need to shake the oral liquid well just before you use it. Follow the directions on the label or ask your pharmacist.
If a dose is missed:
- If you miss a dose or forget to take your medicine, take it as soon as you can. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose.
- Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
- Store the medicine at room temperature, away from heat, moisture, and direct light. Do not freeze.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Avoid drinking alcohol or using any other medicines that make you sleepy. These include sleeping pills, other cold and allergy medicine, narcotic pain relievers, and sedatives.
Warnings While Using This Medicine:
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have heart disease, high blood pressure, diabetes, liver disease, glaucoma, asthma, emphysema, seizure disorder, a disorder of the urinary tract, or an overactive thyroid.
- If your symptoms do not improve within 7 days or if they get worse, call your doctor. If you have a severe sore throat, fever, or thick yellow or green mucus, call your doctor.
- Some brands of this medicine may contain phenylalanine (aspartame). If you have a health problem called phenylketonuria, ask your doctor before using this medicine.
- This medicine can make you drowsy or restless. Avoid taking at bedtime if it makes you restless. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Some brands of this medicine may contain alcohol. Read the label carefully or ask your pharmacist so you know what is in your product.
- Children may be more sensitive to this medicine than adults, especially if they take too much. Always read the medicine label closely so you give your child the right amount. Ask your pharmacist or doctor if you are not sure how much medicine to give your child.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Fast, pounding, or irregular heartbeat
- Severe headache
- Skin rash, hives, or itching
- Trouble breathing
If you notice these less serious side effects, talk with your doctor:
- Dry mouth, nose, or throat
- Trouble urinating
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088Last Updated:
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