Allergy injections; Allergen immunotherapy
What are Allergy Shots?
An allergy shot is a medicine that is injected into your body. The medicine contains a small amount of an allergen. This is a substance that causes an allergic reaction. Examples of allergens include:
A health care provider gives you the shots for 3 to 5 years. This series of allergy shots may help reduce your allergy symptoms.
Work with your provider to identify which allergens are causing your symptoms. This is often done through allergy skin testing or blood tests. Only the allergens you are allergic to are in your allergy shots.
Allergy shots are only 1 part of an allergy treatment plan. You may also take allergy medicines while having allergy shots. Your provider may recommend that you reduce your exposure to allergens, as well.
How do Allergy Shots Work?
Allergy symptoms occur when your immune system tries to attack an allergen in your body. When this happens, your body creates mucus. This can cause bothersome symptoms in the nose, eyes, and lungs.
Treatment with allergy shots is also called immunotherapy. When a small amount of an allergen is injected into your body, your immune system makes a substance called an antibody that blocks the allergen from causing symptoms.
After several months of shots, some or all of your symptoms may be relieved. Relief can last several years. For some people, allergy shots can prevent new allergies and reduce asthma symptoms.
Who can Benefit From Allergy Shots?
You may benefit from allergy shots if you have:
Allergy shots are effective for common allergens such as:
Adults (including the older people) as well as children 5 years and older can receive allergy shots.
Your provider is not likely to recommend allergy shots for you if you:
Food allergies are not treated with allergy shots.
Getting Your Allergy Shots
You will get your allergy shots at your provider's office. They are usually given in the upper arm. The typical schedule is:
Keep in mind that many visits are needed to get the full effects of this treatment. Your provider will assess your symptoms now and then to help decide when you can stop receiving the shots.
An allergy shot may cause a reaction on the skin, such as redness, swelling, and itching. Some people have mild nasal stuffiness or a runny nose.
Though rare, an allergy shot can also cause a severe life-threatening allergic reaction called anaphylaxis. Because of this, you may need to stay in your provider's office for 30 minutes after your shot to check for this reaction.
You may also need to take an antihistamine or another medicine before your allergy shot appointments. This may prevent reactions to the shot at the injection site, but it does not prevent anaphylaxis.
Reactions to allergy shots can be treated in your provider's office right away.
When to Call the Doctor
Call your provider if:
Cox L, Nelson H, Lockey R, et al. Allergen immunotherapy: a practice parameter third update. J Allergy Clin Immunol. 2011;127(1 Suppl):S1-S55. PMID: 21122901 www.ncbi.nlm.nih.gov/pubmed/21122901.
Frew AJ. Allergen immunotherapy. J Allergy Clin Immunol. 2010;125(2 Suppl 2):S306-S313. PMID: 20176266 www.ncbi.nlm.nih.gov/pubmed/20176266.
Golden DBK. Insect allergy. In: Adkinson NF Jr., Bochner BS, Burks AW, et al, eds. Middleton's Allergy: Principles and Practice. 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 78.
Seidman MD, Gurgel RK, Lin SY, et al. Clinical practice guideline: Allergic rhinitis. Otolaryngol Head Neck Surg. 2015;152(1 Suppl):S1-43. PMID: 25644617 www.ncbi.nlm.nih.gov/pubmed/25644617.
Sur DK, Scandale S. Treatment of allergic rhinitis. Am Fam Physician. 2010;81(12):1440-6. PMID: 20540482 www.ncbi.nlm.nih.gov/pubmed/20540482.
Review Date: 10/4/2015
Reviewed By: Stuart I. Henochowicz, MD, FACP, Associate Clinical Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, Georgetown University Medical School, Washington, DC. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
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