Hydrocodone and oxycodone are opioids, drugs that are mostly used to treat extreme pain.
Hydrocodone and oxycodone overdose occurs when someone intentionally or accidentally takes too much medicine containing these ingredients. A person may accidentally take too much of the medicine because they are not getting pain relief from their normal doses. There are several reasons why a person may intentionally take too much of this medicine. It may be done to try to hurt oneself or to get high or intoxicated.
This is for information only and not for use in the treatment or management of an actual overdose. DO NOT use it to treat or manage an actual overdose. If you or someone you are with overdoses, call your local emergency number (such as 911), or your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.
Overdose - hydrocodone; Overdose - oxycodone; Vicodin overdose; Percocet overdose; Percodan overdose; MS Contin overdose; OxyContin overdose
Hydrocodone and oxycodone belong to a class of narcotic medicines called opiates. These medicines are man-made versions of the natural compounds found in opium.
Hydrocodone and oxycodone are most often found in prescription painkillers. The most common painkillers that include these two ingredients are:
These medicines may also be combined with the non-narcotic medicine, acetaminophen (Tylenol).
When you take the correct or prescribed dose of these medicines, side effects may occur. In addition to relieving pain, you may be drowsy, confused and in a daze, constipated, and possibly nauseated.
When you take too much of these medicines, symptoms become much more serious. Symptoms may develop in many body systems:
Eyes, ears, nose, and throat:
Heart and blood vessels:
Before Calling Emergency
The following information is helpful for emergency assistance:
However, DO NOT delay calling for help if this information is not immediately available.
Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This hotline number will let you talk to experts in poisoning. They will give you further instructions.
This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. You can call 24 hours a day, 7 days a week.
What to Expect at the Emergency Room
Take the container with you to the hospital, if possible.
The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated as appropriate. The health care team will closely monitor the person's breathing. The person may receive:
Additional therapies may be needed if the person took hydrocodone and oxycodone with other drugs, such as Tylenol or aspirin.
A large overdose can cause a person to stop breathing and die if not treated right away. The person may need to be admitted to the hospital to continue treatment. Depending on the drug or drugs taken, multiple organs may be affected. This may affect the person's outcome and chances of survival.
If you receive medical attention before serious problems with your breathing occur, you should have few long-term consequences. You will probably be back to normal in a day.
However, this overdose can be deadly or can result in permanent brain damage if treatment is delayed and a large amount of oxycodone and hydrocodone is taken.
Bardsley CH. Opioids. In: Marx JA, Hockberger RS, Walls RM, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 162.
Little M. Toxicology emergencies. In: Cameron P, Jelinek G, Kelly A-M, Brown A, Little M, eds. Textbook of Adult Emergency Medicine. 4th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2015:chap 29.
Pincus MR, Bluth MH, Abraham NZ. Toxicology and therapeutic drug monitoring. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. St Louis, MO: Elsevier; 2017:chap 23.
Zosel AE. General approach to the poisoned patient. In: Adams JG, ed. Emergency Medicine. 2nd ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 143.
Review Date: 1/31/2017
Reviewed By: Jacob L. Heller, MD, MHA, Emergency Medicine, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.