Retinal photography; Eye angiography; Retinopathy - fluorescein
How the Test is Performed
You will be given eye drops that make your pupil dilate. You will be asked to place your chin on a chin rest and your forehead against a support bar to keep your head still during the test.
The health care provider will take pictures of the inside of your eye. After the first group of pictures is taken, a dye called fluorescein is injected into a vein. Most often it is injected at the inside of your elbow. A camera-like device takes pictures as the dye moves through the blood vessels in the back of your eye.
How to Prepare for the Test
You will need someone to drive you home. Your vision may be blurry for up to 12 hours after the test.
You may be told to stop taking medicines that could affect the test results. Tell your provider about any allergies, particularly reactions to iodine.
You must sign an informed consent form. You must remove contact lenses before the test.
Tell the provider if you may be pregnant.
How the Test will Feel
When the needle is inserted, some people feel slight pain. Other others feel only a prick or sting. Afterward, there may be some throbbing.
When the dye is injected, you may have mild nausea and a warm feeling in your body. These symptoms go away quickly most of the time.
The dye will cause your urine to be darker. It may be orange in color for a day or two after the test.
Why the Test is Performed
This test is done to see if there is proper blood flow in the blood vessels in the two layers in the back of your eye (the retina and choroid).
It can also be used to diagnose problems in the eye or to determine how well certain eye treatments are working.
A normal result means the vessels appear a normal size, there are no new abnormal vessels, and there are no blockages or leakages.
What Abnormal Results Mean
If blockage or leakage is present, the pictures will map the location for possible treatment.
An abnormal value on a fluorescein angiography may be due to:
The test may also be done if you have:
There is a slight chance of infection any time the skin is broken. Rarely, a person is overly sensitive to the dye and may experience:
Serious allergic reactions are rare.
The test results are harder to interpret in people with cataracts.
Maguire JI, Federman JL. Intravenous fluorescein angiography. In: Tasman W, Jaeger EA, eds. Duane's Ophthalmology 2013 edition. Philadelphia, PA: Lippincott Williams & Wilkins; 2013:vol 3, chap 4.
Velez-Montoya R, Olson JL, Mandava N. Fluorescein angiography and indocyanine green angiography. In: Yanoff M, Duker JS, eds. Ophthalmology. 4th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 6.6.
Review Date: 8/20/2016
Reviewed By: Franklin W. Lusby, MD, ophthalmologist, Lusby Vision Institute, La Jolla, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.