Alström syndrome is inherited in an autosomal recessive manner. This means both your parents must pass on a copy of the defective gene (ALMS1) in order for you to have this disease.
It is unknown how the defective gene causes the disorder.
The condition is very rare.
Common symptoms of this condition are:
Occasionally, the following can also occur:
Exams and Tests
An eye doctor (ophthalmologist) will examine the eyes. The person may have reduced vision.
Tests may be done to check:
There is no specific treatment for this syndrome. Treatment for symptoms may include:
Alström Syndrome International -- www.alstrom.org
The following are likely to develop:
Kidney and liver failure may get worse.
Possible complications are:
When to Contact a Medical Professional
Call your health care provider if you or your child has symptoms of diabetes. Common symptoms of diabetes are increased thirst and urination. Seek medical attention right away if you think that your child cannot see or hear normally.
Farooqi IS, O'Rahilly S. Genetic syndromes associated with obesity. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 28.
Torres VE, Harris PC. Cystic diseases of the kidney. In: Skorecki K, Chertow GM, Marsden PA, Taal MW, Yu ASL, eds. Brenner and Rector's The Kidney. 10th ed. Philadelphia, PA: Elsevier; 2016:chap 46.
Review Date: 8/31/2016
Reviewed By: Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
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