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Salivary gland infections


Salivary gland infections affect the glands that produce spit (saliva). The infection may be due to bacteria or viruses.

There are 3 pairs of major salivary glands:

  • Parotid glands -- These are the two largest glands. One is located in each cheek over the jaw in front of the ears. Inflammation of one or more of these glands is called parotitis, or parotiditis.
  • Submandibular glands -- These two glands are located just under both sides of the lower jaw and carry saliva up to the floor of the mouth under the tongue.
  • Sublingual glands -- These two glands are located just under the front most area of the floor of the mouth.

All of the salivary glands empty saliva into the mouth. The saliva enters the mouth through ducts that open into the mouth in different places.

Alternative Names

Parotitis; Sialadenitis


Salivary gland infections are somewhat common, and they can return in some people.

Viral infections, such as mumps, often affect the salivary glands. (Mumps most often involves the parotid salivary gland). Mumps is a rare problem today because of the MMR vaccine.

Bacterial infections are most often the result of a:

  • Blockage from salivary duct stones
  • Poor cleanliness in the mouth (oral hygiene)
  • Low amounts of water in the body, most often while in the hospital
  • Smoking
  • Chronic illness


Symptoms include:

Exams and Tests

Your health care provider or dentist will do an exam to look for enlarged glands. You may also have pus that drains into the mouth. The gland is often painful.

A CT scan, MRI scan, or ultrasound may be done if the provider suspects an abscess, or to look for stones.

Your provider may suggest a mumps blood test if multiple glands are involved.


In some cases, no treatment is needed.

Treatment from your provider may include:

  • Antibiotics if you have a fever or pus drainage, or if the infection is caused by bacteria. Antibiotics are not useful against viral infections.
  • Surgery or aspiration to drain an abscess if you have one.
  • A new technique, called sialoendoscopy, uses a very small camera and instruments to diagnose and treat infections and other problems in the salivary glands. 

Self-care steps you can take at home to help with recovery include:

  • Practice good oral hygiene. Brush your teeth and floss well at least twice a day. This may help with healing and prevent an infection from spreading.
  • Rinse your mouth with warm salt water rinses (one half teaspoon or 3 grams of salt in 1 cup or 240 milliliters of water) to ease pain and keep the mouth moist.
  • To speed up healing, stop smoking if you are a smoker.
  • Drink lots of water and use sugar-free lemon drops to increase the flow of saliva and reduce swelling.
  • Massaging the gland with heat.
  • Using warm compresses on the inflamed gland.

Outlook (Prognosis)

Most salivary gland infections go away on their own or are cured with treatment. Some infections will return. Complications are not common.

Possible Complications

Complications may include:

When to Contact a Medical Professional

Call your provider if:

  • You have symptoms of a salivary gland infection.
  • You've been diagnosed with a salivary gland infection and symptoms get worse.
  • Get medical help right away if you have a high fever, trouble breathing, or swallowing problems.


In many cases, salivary gland infections can't be prevented. Good oral hygiene may prevent some cases of bacterial infection.


Elluru RG. Physiology of the salivary glands. In: Flint PW, Haughey BH, Lund V, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 6th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 83.

Jackson NM, Mitchell JL, Walvekar RR. Inflammatory disorders of the salivary glands. In: Flint PW, Haughey BH, Lund V, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 6th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 85.

Review Date: 8/1/2017
Reviewed By: Ashutosh Kacker, MD, FACS, Professor of Clinical Otolaryngology, Weill Cornell Medical College, and Attending Otolaryngologist, New York-Presbyterian Hospital, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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