Acute pancreatitis is sudden swelling and inflammation of the pancreas.
Gallstone pancreatitis; Pancreas - inflammation
The pancreas is an organ located behind the stomach. It produces the hormones insulin and glucagon. It also produces chemicals called enzymes needed to digest food.
Most of the time, the enzymes are only active after they reach the small intestine.
Acute pancreatitis affects men more often than women. Certain diseases, surgeries, and habits make you more likely to develop this condition.
Other conditions that have been linked to pancreatitis are:
Other causes include:
The main symptom of pancreatitis is pain felt in the upper left side or middle of the abdomen. The pain:
People with acute pancreatitis often look ill and have a fever, nausea, vomiting, and sweating.
Other symptoms that may occur with this disease include:
Exams and Tests
The health care provider will do a physical exam, which may show:
Lab tests that show the release of pancreatic enzymes will be done. These include:
Other blood tests that can help diagnose pancreatitis or its complications include:
Imaging tests that can show swelling of the pancreas include:
Treatment often requires a stay in the hospital. It may involve:
A tube may be inserted through the nose or mouth to remove the contents of the stomach. This may be done if vomiting and severe pain do not improve. The tube will stay in for 1 to 2 days to 1 to 2 weeks.
Treating the condition that caused the problem can prevent repeated attacks.
In some cases, therapy is needed to:
In the most severe cases, surgery is needed to remove damaged, dead or infected pancreatic tissue.
Avoid smoking, alcoholic drinks, and fatty foods after the attack has improved.
Most cases go away in a week. However, some cases develop into a life-threatening illness.
The death rate is high with:
Sometimes the swelling and infection do not fully heal. Repeat episodes of pancreatitis may also occur. Either of these can lead to long-term damage of the pancreas.
Pancreatitis can return. The chances of it returning depend on the cause, and how well it can be treated. Complications of acute pancreatitis may include:
When to Contact a Medical Professional
Call your provider if:
You may lower your risk of new or repeat episodes of pancreatitis by taking steps to prevent the medical conditions that can lead to the disease:
Forsmark CE. Pancreatitis. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 144.
Tenner S, Baillie J, DeWitt J, et al. American College of Gastroenterology guideline: management of acute pancreatitis. Am J Gastroenterol. 2013;108:1400-1415. PMID: 23896955 www.ncbi.nlm.nih.gov/pubmed/23896955.
Tenner S, Steinbert WM. Acute pancreatitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger & Fordtran's Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 58.
Review Date: 10/27/2015
Reviewed By: Subodh K. Lal, MD, gastroenterologist with Gastrointestinal Specialists of Georgia, Austell, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
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