Atrial septal defect (ASD)
Atrial septal defect (ASD) is a heart defect that is present at birth (congenital).
As a baby develops in the womb, a wall (septum) forms that divides the upper chamber into a left and right atrium. An abnormal formation of this wall can result in a defect that remains after birth. This is called an atrial septal defect, or ASD.
Congenital heart defect - ASD; Birth defect heart - ASD; Primum ASD; Secundum ASD
Normally, blood cannot flow between the two upper heart chambers. However, an ASD allows this to happen.
When blood flows between the two heart chambers. This is called a shunt. Pressure in the lungs may build up. Over time, there will be less oxygen in the blood that goes to the body.
Atrial septal defects are defined as primum or secundum.
Very small defects of (less than 5 millimeters or ¼ inch) are less likely to cause problems. Smaller defects are often discovered much later in life than larger ones.
Along with the size of the ASD, where the defect is located plays a role on blood flow and oxygen levels. The presence of other heart defects is also important.
ASD is not very common.
A person with no other heart defect, or a small defect (less than 5 millimeters) may not have any symptoms, or symptoms may not occur until middle age or later.
Symptoms that do occur may begin at any time after birth through childhood. They can include:
Exams and Tests
The health care provider will check how large and severe an ASD is based on the symptoms, physical exam, and the results of heart tests.
The provider may hear abnormal heart sounds when listening to the chest with a stethoscope. A murmur may be heard only in certain body positions. Sometimes, a murmur may not be heard at all. A murmur means that blood is not flowing through the heart smoothly.
The physical exam may also show signs of heart failure in some adults.
An echocardiogram is a test that uses sound waves to create a moving picture of the heart. It is often the first test done. A Doppler study done at the same time as an echocardiogram allows the health care provider to assess the amount of shunting of blood between the heart chambers.
Other tests that may be done include:
ASD may not need treatment if there are few or no symptoms, or if the defect is small and is not associated with other abnormalities. Surgery to close the defect is recommended if the defect causes a large amount of shunting, the heart is swollen, or symptoms occur.
A procedure has been developed to close the defect without surgery.
Sometimes, open-heart surgery may be needed to repair the defect. The type of surgery is more likely needed when other heart defects are present.
Some people with atrial septal defects may be able to have this procedure, depending on the size and location of the defect.
People who have surgery for ASD should get antibiotics before any dental procedures they have in the period following the procedure. Antibiotics are not needed later on.
In infants, small ASDs (less than 5 mm) will often not cause problems, or will close without treatment. Larger ASDs (8 to 10 mm), often do not close and may need a procedure.
Important factors include the size of the defect, the amount of extra blood flowing through the opening, and whether the person has any symptoms.
Some people with ASD may have other congenital heart conditions. These may include a leaky valve or a hole in another area of the heart.
People with a larger or more complicated ASD are at an increased risk for developing other problems, including:
When to Contact a Medical Professional
Call your health care provider if you have symptoms of an atrial septal defect.
There is no known way to prevent the defect. Some of the complications can be prevented with early detection.
Geva T, Martins JD, Wald RM. Atrial septal defects. Lancet. 2014;383(9932):1921-1932. PMID: 24725467 www.ncbi.nlm.nih.gov/pubmed/24725467.
Hanslik A, Pospisil U, Salzer-Muhar U, Greber-Platzer S, Male C. Predictors of spontaneous closure of isolated secundum atrial septal defect in children: a longitudinal study. Pediatrics. 2006;118(4):1560-1565. PMID: 17015547 www.ncbi.nlm.nih.gov/pubmed/17015547.
Marelli AJ. Congenital heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 69.
Silvestry FE, Cohen MS, Armsby LB, et al. Guidelines for the echocardiographic assessment of atrial septal defect and patent foramen ovale: from the American Society of Echocardiography and Society for Cardiac Angiography and Interventions. J Am Soc Echocardiogr. 2015;28(8):910-958. PMID: 26239900 www.ncbi.nlm.nih.gov/pubmed/26239900.
Webb GD, Smallhorn JF, Therrien J, Redington AN. Congenital heart disease. In: Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 10th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 62.
Review Date: 1/19/2016
Reviewed By: Larry A. Weinrauch MD, Assistant Professor of Medicine, Harvard Medical School, Cardiovascular Disease and Clinical Outcomes Research, Watertown, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.