Ventricular septal defect
Ventricular septal defect is a hole in the wall that separates the right and left ventricles of the heart. Ventricular septal defect is one of the most common congenital (present from birth) heart defects. It may occur by itself or with other congenital diseases.
VSD; Interventricular septal defect; Congenital heart defect - VSD
Before a baby is born, the right and left ventricles of its heart are not separate. As the fetus grows, a wall forms to separate these 2 ventricles. If the wall does not completely form, a hole remains. This hole is known as a ventricular septal defect, or a VSD.
Ventricular septal defect is a common congenital heart defect. The baby may have no symptoms and the hole can close over time as the wall continues to grow after birth. If the hole is large, too much blood will be pumped to the lungs. This can lead to heart failure.
The cause of VSD is not yet known. This defect often occurs along with other congenital heart defects.
In adults, ventricular septal defects are a rare but serious complication of heart attacks. These holes do not result from a birth defect.
People with ventricular septal defects may not have symptoms. However, if the hole is large, the baby often has symptoms related to heart failure.
The most common symptoms include:
Exams and Tests
Listening with a stethoscope most often reveals a heart murmur. The loudness of the murmur is related to the size of the defect and amount of blood crossing the defect.
Tests may include:
If the defect is small, no treatment may be needed. But the baby should be closely monitored by a health care provider. This is to make sure that the hole eventually closes properly and signs of heart failure do not occur.
Babies with a large VSD who have symptoms related to heart failure may need medicine to control the symptoms and surgery to close the hole. Medicines may include digitalis (digoxin) and diuretics.
If symptoms continue, even with medicine, surgery to close the defect with a patch is needed. Some VSDs can be closed with a special device during a cardiac catheterization, which avoids the need for surgery. However, only certain types of defects can successfully be treated this way.
Having surgery for a VSD with no symptoms is controversial. Discuss this carefully with your provider.
Many small defects will close on their own. Surgery can repair defects that do not close. In most cases, a person will not have any ongoing medical issues related to the defect if it is closed with surgery or closes on its own. Complications may occur if a large defect is not treated.
Complications may include:
When to Contact a Medical Professional
Most often, this condition is diagnosed during routine exam of an infant. Call your infant's provider if the baby seems to be having trouble breathing, or if the baby seems to have an unusual number of respiratory infections.
Except for VSD that is caused by a heart attack, this condition is always present at birth.
Drinking alcohol and using the antiseizure medicines depakote and dilantin during pregnancy may increase the risk for VSDs. Other than avoiding these things during pregnancy, there is no known way to prevent a VSD.
Fraser CD, Carberry KE. Congenital heart disease. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 19th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 59.
Webb GD, Smallhorn JF, Therrien J, Redington AN. Congenital heart disease. In: Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 10th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 62.
Review Date: 10/22/2015
Reviewed By: Larry A. Weinrauch, MD, Assistant Professor of Medicine, Harvard Medical School, Cardiovascular Disease and Clinical Outcomes Research, Watertown, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
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