Endometrial biopsy is the removal of a small piece of tissue from the lining of the uterus (endometrium) for examination.
Biopsy - endometrium
How the Test is Performed
This procedure may be done with or without anesthesia. This is medicine that allows you to sleep during the procedure.
How to Prepare for the Test
Before the test:
How the Test will Feel
The instruments may feel cold. You may feel some cramping when the cervix is grasped. You may have some mild cramping as the instruments enter the uterus and the sample is collected.
Why the Test is Performed
The test is done to find the cause of:
The biopsy is normal if the cells in the sample are not abnormal.
What Abnormal Results Mean
Abnormal menstrual periods may be caused by:
Other conditions under which the test may be performed:
Risks of endometrial biopsy include:
Beard JM, Osborn J. Common office procedures. In: Rakel RE, Rakel DP, eds. Textbook of Family Medicine. 9th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 28.
Soliman PT, Lu KH. Neoplastic diseases of the uterus: endometrial hyperplasia, endometrial carcinoma, sarcoma: diagnosis and management. In: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Comprehensive Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 32.
Review Date: 7/17/2017
Reviewed By: Cynthia D. White, MD, Fellow American College of Obstetricians and Gynecologists, Group Health Cooperative, Bellevue, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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