Renal pelvis or ureter cancer
Cancer of the renal pelvis or ureter is cancer that forms in the kidney's pelvis or the tube (ureter) that carries urine from the kidney to the bladder.
Transitional cell cancer of the renal pelvis or ureter; Kidney cancer - renal pelvis; Ureter cancer
Cancer can grow in the urine collection system, but it is uncommon. Renal pelvis and ureter cancers affect men more often than women. These cancers are more common in people older than 65.
The exact causes of this cancer are not known. Long-term (chronic) irritation of the kidney from harmful substances removed in the urine may be a factor. This irritation may be caused by:
People who have had bladder cancer are also at risk.
Symptoms may include any of the following:
Exams and Tests
The health care provider will perform a physical exam, and examine your belly area (abdomen). In rare cases, this may reveal an enlarged kidney.
If tests are done:
Other tests that may be ordered include:
These tests may reveal a tumor or show that the cancer has spread from the kidneys.
The goal of treatment is to eliminate the cancer.
Surgery to remove all or part of the kidney (nephrectomy) is often done. This may include removing part of the bladder and tissues around it, or the lymph nodes. If the tumor is in the ureter, it may be possible to remove it while preserving the kidney.
When the cancer has spread outside of the kidney or ureter, chemotherapy is often used. Because these tumors are similar to a form of bladder cancer, they are treated with a similar type of chemotherapy.
You can ease the stress of illness by joining a cancer support group. Sharing with others who have common experiences and problems can help you not feel alone.
Outcome varies depending on the location of the tumor and whether the cancer has spread. Cancer that is only in the kidney or ureter may be cured with surgery.
Cancer that has spread to other organs is usually not curable.
Complications from this cancer may include:
When to Contact a Medical Professional
Contact your provider if you have any of the symptoms listed above.
Measures that may help prevent this cancer include:
National Cancer Institute website. Transitional cell cancer (kidney/ureter) treatment (PDQ) - health professional version. www.cancer.gov/types/kidney/hp/transitional-cell-treatment-pdq. Updated October 7, 2018. Accessed March 8, 2018.
National Comprehensive Cancer Network website. NCCN clinical practice guidelines in oncology (NCCN guidelines) kidney cancer. Version 3.2018. www.nccn.org/professionals/physician_gls/pdf/kidney.pdf. Updated February 6, 2018. Accessed March 8, 2018.
Pili R, Kauffman E, Rodriguez R. Cancer of the kidney. In: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff's Clinical Oncology. 5th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2014:chap 82.
Review Date: 5/20/2016
Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Editorial update 03/08/2018.
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